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Comorbid Social Dysfunction

Written by Il Hwan Kim

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“Social Processes” is a major behavioral domain for study in the RDoC Matrix (https://www.nimh.nih.gov/research-priorities/rdoc/constructs/rdoc-matrix.shtml). Alterations in social behaviors are features of communication disorders, certain anxiety disorders, ASD, and SZ. Human genetic studies with patients displaying social dysfunction have identified various polymorphisms associated with these abnormalities. Similarly, a number of different mouse inbred strains as well… Read More

Brain Circuits of Psychiatric Disorders

Written by Il Hwan Kim

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Welcome to Kim Lab. My lab focuses on a fundamental question in psychiatry: “how do disparate mutations lead to similar neuropsychiatric behavioral symptoms?” To address this question, we have been investigating neural circuit pathologies that drive comorbid endophenotypes associated with psychiatric disorders including schizophrenia (SZ) and autism-spectrum disorder (ASD). The central hypothesis of our research… Read More